Careful Interpretation of HLA Typing and Cross-Match Tests in Kidney Transplant
نویسنده
چکیده
Mohanka R1,2, El Kosi M2,3, Jin JK2,4, Sharma A2,5 and Halawa A2,6* 1Depatment of Hepato-Biliary Surgery and Transplantation, Global Hospital, Mumbai, India 2Department of Health and Science, University of Liverpool, UK 3Doncaster Royal Infirmary, UK 4Nottingham Children Hospital, UK 5Royal Liverpool University Hospitals, UK 6Sheffield Teaching Hospitals, UK Submission: July 03, 2017; Published: August 04, 2017 *Corresponding author: Ahmed Halawa, Consultant Transplant Surgeon, Sheffield Teaching Hospital,United Kingdom, Tel: ; Fax: +441142714604; Email:
منابع مشابه
The Sensitized Candidate in Renal Transplantation*
New strategies involving patient selection, desensitization, and post-transplantation immunosuppression have improved the outlook for many patients who are sensitized to human leukocyte antigens (HLAs). For example, new methods of cross-match analysis that go beyond the traditional panel reactive antibodies (PRAs) are allowing some sensitized patients to advance with reasonable safety to transp...
متن کاملHigh-Resolution HLA-A Typing in Normal Iranian Population
Background: Human leukocyte antigen (HLA) gene is a highly polymorphic region. HLA typing is required to match patients and donors for transplantation; therefore, development of HLA registries is necessary for finding HLA match donors. HLA system is highly informative, and numerous studies have been conducted on HLA allele distribution in different populations. Methods: In this study,...
متن کاملTyping of HLA Class I by Polymerase Chain Reaction-Sequence Specific Oligonucleotide Primer (PCR-SSOP) Technique in Iranian Cord Blood Donors
Background: HLA compatibility between transplant donor and recipient is one of the major determinants of transplant outcome. Objective: To determine HLA class I by PCR- Sequence-Specific Oligonucleotide Probe (PCR-SSOP) in cord blood donors. Methods: Genomic DNA of 142 cord blood samples registered at the Cord Blood Bank of Iran at Hematology, Oncology, and Bone Marrow Transplantation Researc...
متن کاملIdentification of HLA Class I Misreads/Dropouts Using Serological Typing, in Comparison with DNA-based Typing.
Serology and DNA techniques are employed for Human Leukocyte Antigen (HLA) typing in different transplant centers. Results may not always correlate well and may need retyping with different technique. All the patients (with aplastic anemia, thalassemia, and immunodeficiency) and their donors, requiring HLA typing for bone marrow transplant were enrolled in the study. Serological HLA typing was ...
متن کاملHuman leukocyte antigen variation among Iranian renal transplant recipients.
BACKGROUND HLA typing analysis is important in renal transplant patients. OBJECTIVES We made a plan to determine the most frequent HLA antigens in Iranian kidney transplant patients. PATIENTS AND METHODS In a retrospective cross sectional study, HLA patterns were defined in 512 kidney transplant recipients (67% male and 33% female) from different transplant centers of Tehran, Iran between 2...
متن کامل